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Decade: 2010-2019
Year: 2011
Issue: Vol 14 | No. 6 | December 2011 | Pages 251-296
Search Within This Issue
4 Articles:
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Editorial Board
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Slipping and sliding: Frameshift mutations in herpes simplex virus thymidine kinase and drug-resistance
23 September 2011
Highlights: ► Although acyclovir and related compounds are effective herpes simplex virus therapies, drug resistance is an important clinical problem. ► Frameshift mutations in the viral thymidine kin...
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Anthony Griffiths
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251-259
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Protein-intrinsic and signaling network-based sources of resistance to EGFR- and ErbB family-targeted therapies in head and neck cancer
19 September 2011
Highlights: ► Although inhibition of EGFR and other ERBB-family proteins is a standard approach in cancer, diverse resistance mechanisms limit efficacy of this strategy. ► We summarize current and dev...
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Ranee Mehra,
Ilya G. Serebriiskii,
Roland L. Dunbrack,
Matthew K. Robinson,
Barbara Burtness,
Erica A. Golemis
et al.
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260-279
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Epigenetics and chemoresistance in colorectal cancer: An opportunity for treatment tailoring and novel therapeutic strategies
28 September 2011
Highlights: ► Colorectal cancer (CRC) is the second cause of cancer-related deaths in the world. ► Despite therapeutic advancements, CRC drug resistance is the main cause of treatment failure. ► Epige...
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Francesco Crea,
Stefania Nobili,
Elisa Paolicchi,
Gabriele Perrone,
Cristina Napoli,
Ida Landini,
Romano Danesi,
Enrico Mini
et al.
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280-296
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